Download An Introduction to Neuroendocrinology by Michael Wilkinson PDF

By Michael Wilkinson

ISBN-10: 052180647X

ISBN-13: 9780521806473

How does the mind keep an eye on sexual habit, or keep watch over our bodyweight? How can we focus on tension? Addressing those questions and plenty of extra in addition to, this completely revised new version displays the numerous advances which were made within the research of neuroendocrinology over the past 20 years. The textual content examines the significance of the hypothalamus in regulating hormone secretion from the endocrine glands, describing novel websites of hormone free up together with bone, middle, skeletal muscle and liver. The function of steroid hormone, neurotransmitter and peptide receptors, and the molecular responses of goal tissues, is built-in into the dialogue of the neuroendocrine mind, in particular via adjustments in gene expression. specific cognizance is connected to neuropeptides, together with their profound impression on habit. entire with new full-color figures all through, besides evaluate and essay questions for every bankruptcy, this is often an amazing source for undergraduate and graduate scholars of neuroscience, psychology, biology and body structure.

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A large number of growth factors are now known, but three of the most familiar are nerve growth factor (NGF), which is synthesized in innervated structures such as the heart and brain; epidermal growth factor (EGF), which is synthesized in the salivary glands; and fibroblast growth factor (FGF), which is synthesized throughout the neural and endocrine systems. Growth factors tend to act locally, in an autocrine/paracrine fashion, although there is now evidence that some may also be intracrine messengers.

On the other hand, it is a well-described neuropeptide acting within the brain and spinal cord. Abbreviations: ACTH, adrenocorticotropic hormone; BDNF, brain-derived neurotrophic factor; CCK, cholecystokinin; CRH, corticotropin-releasing hormone; EGF, epidermal growth factor; FGF, fibroblast growth factor; FSH, follicle-stimulating hormone; GABA, gamma-aminobutyric acid; GnRH, gonadotropin-releasing hormone; LH, luteinizing hormone; NGF, nerve growth factor; TGFα, transforming growth factor α; TRH, thyrotropin-releasing hormone; TSH, thyroid-stimulating hormone; VIP, vasoactive intestinal polypeptide.

During pregnancy, the placenta acts as an endocrine gland. The endocrine glands occur in similar locations in all vertebrates. 1), and within tissues such as liver and muscle. Fat secretes a variety of hormones called adipokines. Finally, two of the largest tissues in the body – skeletal muscle and bone – secrete factors that act in an endocrine fashion. 2 The hormones of the endocrine glands Each endocrine gland secretes one or more hormones. 1 summarizes the main hormones produced by each gland and some of the functions of these hormones.

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