Download Advances in Molecular and Cell Biology by E. Edward Bittar (Eds.) PDF

By E. Edward Bittar (Eds.)

ISBN-10: 1559382090

ISBN-13: 9781559382090

The fourth quantity of the ''Advances in Molecular and mobile Biology'' sequence. mobilephone biology is a rapidly-developing self-discipline, bringing jointly many separate organic sciences. The interrelations of telephone constitution and serve as at molecular and subcellular degrees are the principal subject of the sequence

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Autoantibody studies have also identified proteins that are distributed throughout the chromosome including the centromere. Examples of this type of protein is topoisomerase I1 which has been identified as a major scaffold protein (Earnshaw and Heck, 1985). Antibody binding studies indicate that it is found throughout the 250 nm chromatin fiber. Although its exact distribution within the fiber remains unclear, it seems likely that this protein is a major component of the central domain. In addition to ubiquitous structural proteins, there are proteins that have a transient association with the centromere in a cell-cycle dependent manner.

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