Download A History of Biochemistry: Selected Topics in the History of by Albert Neuberger, L. L. M. Van Deenen, Giorgio Semenza PDF

By Albert Neuberger, L. L. M. Van Deenen, Giorgio Semenza

ISBN-10: 0444807020

ISBN-13: 9780444807021

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ATP HC03orC02 H2N OJPOCH 2 \ '^0 K + Mg t+ · il OH AMINOIMIDAZOLE RIBOTIDE GLUTAMATE GLUTAMINE +AOP+HPO; +ATPf H20 CH / Mg + + TH OH OH OH GLYCINAMIDE RIBOTIDE NH 0-jPOCH. N-C 03POCH: N \>0\/ /v> 1 Γ OH M N ^ CH COO // ASPARTATE A DP +ATP +ΗΡΟΪ W FUMARATE H2N / N -FORMYL-THFA O;POCH? H/\ 1 H OH 5-AMIN0-4-IMIDAZ0LECARB0XYLIC ACID RIBOTIDE OH OH 5-AMINO-4-IMI0AZOLE-N-SUCCINOCARBOXAMIDE RIBOTIDE HN- / HC N OiPOCH- CH X N ^ OH OH INOSINIC ACID OH OH 5-F0RMAMID0-4-IMIDAZ0LECARB0XAMIDE RIBOTIDE Fig.

2). This finding was followed within a short time by A BACKWARD GLANCE 23 GLUTAMINE GLUTAMATE +H2O +HP2O"; 03POCH io^f H OH O;POCH. OjPOCH. H V — - f 01 OH ' ° OH OH 5-PHOSPHORIBOSYLPYROPHOSPHATE . \ ATP HC03orC02 H2N OJPOCH 2 \ '^0 K + Mg t+ · il OH AMINOIMIDAZOLE RIBOTIDE GLUTAMATE GLUTAMINE +AOP+HPO; +ATPf H20 CH / Mg + + TH OH OH OH GLYCINAMIDE RIBOTIDE NH 0-jPOCH. N-C 03POCH: N \>0\/ /v> 1 Γ OH M N ^ CH COO // ASPARTATE A DP +ATP +ΗΡΟΪ W FUMARATE H2N / N -FORMYL-THFA O;POCH? H/\ 1 H OH 5-AMIN0-4-IMIDAZ0LECARB0XYLIC ACID RIBOTIDE OH OH 5-AMINO-4-IMI0AZOLE-N-SUCCINOCARBOXAMIDE RIBOTIDE HN- / HC N OiPOCH- CH X N ^ OH OH INOSINIC ACID OH OH 5-F0RMAMID0-4-IMIDAZ0LECARB0XAMIDE RIBOTIDE Fig.

Three such radioactive proteins were formed from radioactive leucine and identified by polyacrylamide gel electrophoresis. The role of FST-DNA in preparing the host cells for the synthesis of several enzymes (or class II functions) was then demonstrated. Cells that had carried out the FST reaction at 37° C were capable of initiating enzyme synthesis immediately. Cells held at 0°C during this period required a 10- to 12-min delay. In subsequent research [229-236] Richard Moyer, David Sirbasku and Jaakko Pispa clearly defined the types of proteins and RNA formed during the entire infection period and the role of calcium ions in these first initial reactions.

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