By William W. Cohen
This sensible consultant offers a succinct remedy of the overall suggestions of telephone biology, furnishing the pc scientist with the instruments essential to learn and comprehend present literature within the field.
The ebook explores 3 diversified points of biology: biological platforms, experimental methods, and language and nomenclature. After a short advent to cellphone biology, the textual content makes a speciality of the rules in the back of the most-widely used experimental strategies and mechanisms, concerning them to well-understood strategies in machine technology.
The presentation of the fabric has been ready for the reader’s quickly seize of the subject: reviews on nomenclature and heritage notes may be ascertained at a look, and crucial vocabulary is boldfaced through the textual content for simple identification.
Computer technology researchers, pros and machine technology scholars will locate this an incomparable source and a very good place to begin for a extra accomplished exam of mobile biology.
"This concise booklet is a superb creation for laptop scientists to the interesting revolution lower than means in molecular biology. It offers lucid, high-level descriptions of the elemental molecular mechanisms of existence, and discusses the computational rules concerned. I want this little gem used to be to be had while i used to be ‘learning the ropes’– it will were my first collection of interpreting material."
--Roni Rosenfeld, Carnegie Mellon University
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Extra resources for A Computer Scientist's Guide to Cell Biology: A travelogue from a stranger in a strange land
The aperature (width) of the microscope limits the angle between these to some θMAX and solving the equation above implies p > λ/sin θMAX Unless this holds, the two pinholes cannot be resolved. Figure 21. The Abbe model of resolution. William W. Cohen 39 (The figure ignores the issue of refractive index, which is the ratio of speed of light in the medium containing the specimen to the speed of light in air. 5 micrometers (µm), and objects smaller than 2 µm cannot be resolved even with the best light microscopes.
Cohen 51 environments—for instance, different nutrients, or different temperatures. In a multi-celled organism, cells from different tissues express different sets of proteins. Studying such differences in genetic expression is a frequent goal in experimental biology. Since proteins are always encoded by mRNA before they are built, one (indirect) way to detect differences in the proteomes of two cells is to compare their sets of mRNAs. ” The base complementary to adenine is thymine, abbreviated “T,” and hence most mRNA will easily hybridize to a nucleic acid that consists of a long sequence of thymine residues.
Medium being used, is called This limit is imposed by the wave- the numerical aperture of a length of light. The wave nature of microscope. Making the aperture wider improves light implies that light waves interfere resolution at the cost of depth with each other, which distorts images: of field. for instance, a point source of light will appear as a circle surrounded by a series of concentric circles. For some simple objects, one can precisely analyze the result of interference, and make precise claims about what can and what cannot be seen.